Here's a simple example of a start button in a graphical user interface (GUI) using Python and the Tkinter library. When you click the start button, it disappears from the screen:

python
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import tkinter as tk

def start_button_clicked():
    start_button.pack_forget()  # Remove the start button
    label.pack()  # Display a label after clicking the start button

root = tk.Tk()
root.title("Start Button Example")

start_button = tk.Button(root, text="Start", command=start_button_clicked)
label = tk.Label(root, text="Start button clicked!")

start_button.pack()

root.mainloop()